After spending some time in the US Army, in 1964 he joined Maurice McAlister, a fellow member of the Greater Harvest Church, in his vocal group, The Radiants.
[3] Caston left the Radiants in 1965, after their first two hit singles, "Voice Your Choice" and "It Ain't No Big Thing", and began working as a session musician, songwriter and producer at Chess.
[3] He played piano on Fontella Bass' hit "Rescue Me",[4] and also worked with singers Bobby McClure, Jan Bradley and Laura Lee.
[3] Caston left Chess in 1968, and joined Motown Records in Detroit, where he worked with songwriter Kathy Wakefield, and writer and producer Frank Wilson.
Caston then worked with co-producer Wilson and co-writer Anita Poree to revive the career of ex-Temptations lead singer Eddie Kendricks.
In 2002, Caston won a Billboard BMI Urban Music Award, and in 2004 he co-produced, with Billy Davis, the album 19 Days in New York by Australian singer Kate Ceberano.