Griffin distinguished himself at the school, helping the team win a national championship in 2002, and being named an NCAA All-American in 2003.

In his first year Griffin had trouble establishing himself in a single role, but instead played a variety of defensive positions for the Fire when needed, finishing with 330 minutes over 9 games.

Griffin was waived by the Fire during the 2007 pre-season, and signed by USL First Division side Portland Timbers, joining former UCLA teammate and fellow defensive standout Scot Thompson.

Griffin was signed by Los Angeles Galaxy on January 7, 2009, but suffered an injury in pre-season which prevented him from playing.

Upon his recovery, and with the MLS Reserve Division having been scrapped at the end of 2008, Galaxy loaned Griffin to the Hollywood United Hitmen of the USL Premier Development League for part of the 2009 PDL season, to regain his match fitness levels.

[4] In April 2019 he was announced as the new head coach for the San Francisco Dons men's soccer team, replacing Eddie Soto who resigned as the prior month.