Leonardo Piepoli (born 29 September 1971 in La Chaux-de-Fonds, Switzerland) is a former Italian professional road racing cyclist.

He most recently rode for Saunier Duval–Scott on the UCI ProTour, but had his contract suspended in July 2008 during the Tour de France amid allegations of the use of the blood boosting drug EPO in the team.

Piepoli is a specialist climber, and this was shown in the 2006 Giro d'Italia, where he was one of the strongest riders in the mountains and won two stages.

Before the twelfth stage, Piepoli and the rest of his team stepped out of the race, after Riccò had tested positive for doping.

[2] In a 7 January 2009 interview with the Italian newspaper Gazzetta dello Sport, Piepoli acknowledged that he had used CERA in "a moment of weakness".