With the death of her fourth husband in 1527, Cortés, the ruler of New Spain moved her into his palace and, shortly, she became pregnant with her first child.
Doña Leonor was separated from her mother and raised in the household of Juan Gutiérrez de Altamirano.
Her father, Hernán Cortés, died in 1547 in Spain, leaving her 10,000 ducats and her mother Doña Isabel Moctezuma gave her part of her estate, apparently reconciled with her out-of-wedlock daughter.
[2] She accepted marriage with Juan de Tolosa, one of the discoverers of the silver mines and founders of the city of Zacatecas in 1546.
The couple had at least three children : The date of Doña Leonor's death is unknown, although apparently she died before 1594, as did her husband.