The society began with an initiative of Bishop Fenwick of Cincinnati, who sent Frederick Rese, his vicar-general, to Europe to recruit German priests to minister to the German-speaking Catholics who had emigrated to Ohio.
At this time, in 1827, Bishop Edward Fenwick of Cincinnati, Ohio sent his vicar-general, Father Rese, to Europe to recruit German priests and to obtain assistance for his diocese.
The Archbishop of Vienna, Leopold Maximilian Graf von Firmian, was so well disposed towards this undertaking that he brought it to the notice of the imperial family.
Father Rese was granted an audience with the emperor, whose brother, Archduke Rudolf von Habsburg-Lothringen, Cardinal Archbishop of Olmutz, assumed the protectorate of the missionary work.
Canon Joseph Pletz, of the Metropolitan Church of St. Stephen, spoke on the propagation of the Gospel and what he saw as its civilizing influences upon the nations of the world.
On 30 April 1830, a first draft of $10,256.04 was sent to Bishop Fenwick and four months later a second one of $5200, "to afford ample help and not to deal out the money in small bits and give relief practically to nobody".
[5] The general interest awakened by the society for the American missions not only brought out funds but donations of church utensils, Mass paraphernalia, paintings, statuary, etc.
Among the older ones Cincinnati has been most helped, but St. Louis, Bardstown, Charleston, Philadelphia, Baltimore, Mobile, Boston, Detroit, New York, New Orleans, Nashville, Dubuque, Natchez, Vincennes, Richmond, Pittsburg, Chicago, St. Paul, Hartford, Milwaukee, Marquette, Galveston, Little Rock, received generous support.
Official reports, Berichte der Leopoldinen Stiftung, appeared, detailing the struggles and successes of the American missions and missionaries.