[1][2] This frog is found in central and southeastern Brazil, northeast Argentina (Misiones and Corrientes Provinces), and eastern Paraguay.

[6][7] The eggs of L. labyrinthicus are laid in foam nests, often in burrows on dry land or in swampy soil near water.

It is hypothesized that the male frog finds or possibly creates the burrow in a suitable location and uses it as shelter during the reproductive season.

L. labyrinthicus tadpoles are mostly active at night, and hide from visual predators (including birds such as the creamy-bellied thrush) during the day by burrowing in gravel and leaves.

It is harvested in Venezuela, and attempts have been made to establish farms for commercial production in Brazil (although these failed for managerial reasons).