Les Eyzies-de-Tayac-Sireuil (French pronunciation: [le.z‿ezi də tajak siʁœj]; Occitan: Las Aisiás de Taiac e Siruèlh) is a former commune in the Dordogne department in Nouvelle-Aquitaine in southwestern France.

This locale is home to the Musée national de Préhistoire [fr] (National Museum of Prehistory) and the area contains several important archaeological sites, including the Font-de-Gaume, Grotte du Grand-Roc [fr] and Lascaux cave prehistoric rock dwellings.

These skeletons included a foetus, and the skulls found were remarkably modern-looking and much rounder than the earlier Neanderthal.

As at 31 December 2013, the municipality has 209 establishments, including 151 in the field of commerce, transport or services, twenty relating to the administrative sector, education, health or social action, eighteen in construction, thirteen in the industry, and seven in agriculture, forestry or fishing.

[4] The discovery of these shelters within a restricted radius around Les Eyzies, their methodical exploration and the study of the deposits they concealed allowed prehistory to build up as a science and explains why the city claims the status of world capital of the prehistory, as the publicity leaflets recall.