Les Ponts-de-Cé (French pronunciation: [le pɔ̃ də se] ⓘ) is a commune in the Maine-et-Loire department in western France.

In September 1432, during the Hundred Years' War, the routiers of Rodrigo de Villandrando, in the pay of Georges de la Trémoille, held Les Ponts-de-Cé against the assaults of Jean de Bueil.

On 7 August 1620, the Battle of Ponts-de-Cé definitively ended a civil war, waged by Marie de Médicis.

Her troops were defeated by her son, the French King Louis XIII.

This short rebellion, subdued easily by the King's troops, is known in France under the name of "Drôlerie des Ponts-de-Cé" (Les Ponts-de-Cé's joke).