Leslie is a village in west central Franklin County, Missouri, United States.

[4] According to the United States Census Bureau, the village has a total area of 0.17 square miles (0.44 km2), all land.

The racial make-up of the village was 96.5% White, 0.6% Native American and 2.9% from two or more races.

18.0% of all households were made up of individuals and 2% had someone living alone who was 65 years of age or older.

37.1% of all households were made up of individuals and 22.9% had someone living alone who was 65 years of age or older.

There were 15.8% of families and 12.4% of the population living below the poverty line, including no under eighteens and 22.2% of those over 64.