Lespignan (French pronunciation: [lɛspiɲɑ̃]; Occitan: Lespinhan) is a commune in the Hérault département in the Occitanie region in southern France.

The average annual rainfall is 620.7 mm (24.44 in) with October as the wettest month.

Excavations indicate human habitation of Lespignan dating to 4000 years ago.

[4] In 1379 King Charles V used his right of preemption to officially establish Lespignan as a community.

[4] In 1500, the village acquired its own lord through a treaty of joint sovereignty with King Charles V.[4] The absence of a male heir led to successive changes in leadership.