The Lesser Poland Gorge of the Vistula (Polish: Małopolski Przełom Wisły) is a geographical region located in central-eastern Poland, which administratively belongs to three Polish voivodeships – Lublin, Masovian, and Świętokrzyskie.

The gorge is about 70 kilometers long, extending from the town of Zawichost in the south, to Puławy in the north.

In some places, the banks of the Vistula valley are very steep, up to 70 meters above the water level.

The region comprises a densely populated agricultural land, with two main towns; historic Kazimierz Dolny, and Annopol.

The Gorge is one of several protected areas designated in the Natura 2000 territory of the European Union's ecological network around the Vistula and Pilica rivers (out of the total of around 500 Natura 2000 sites in Poland).