Let’s Play Fats Domino is a 1959 studio album by American rock and roll pianist Fats Domino, released on Imperial Records.

A contemporary review in Billboard highlighted how many hits the album had and its strong New Orleans sound.

[1] The New Rolling Stone Album Guide scores this release alongside all of Domino's Imperial albums as 4.5 out of five stars.

[2] The editorial staff of AllMusic Guide scored this album 3.5 out of five stars, with reviewer Stephen Thomas Erlewine characterizing it as a "terrifically entertaining listen" and summing up his review "maybe it's not the best Fats Domino album ever, but as it's playing it's hard to imagine listening to anything better than this".

[3] All songs written by Dave Bartholomew and Fats Domino, except where noted.