Lettere is a comune (municipality) in the Metropolitan City of Naples in the southern central Italian region Campania, located about 30 km southeast of Naples.

Lettere borders the following municipalities: Angri, Casola di Napoli, Corbara, Gragnano, Ravello, Sant'Antonio Abate, Tramonti.

From 987 it was the see of a bishopric, which was renamed Roman Catholic Diocese of Lettere-Gragnano (viz.)

from 1169 till its merger into the Diocese of Castellammare di Stabia.

In 1968 it was nominally restored as Latin Titular bishopric of Lettere.