Leuze-en-Hainaut (French pronunciation: [løz ɑ̃ ɛno] ⓘ; Picard: Leuze-in-Hénau; Walloon: Leuze-e-Hinnot) is a city and municipality of Wallonia located in the province of Hainaut, Belgium.

On 1 January 2018, it had a population of 13,886.

The municipality consists of the following districts: Blicquy, Chapelle-à-Oie, Chapelle-à-Wattines, Gallaix, Grandmetz, Leuze-en-Hainaut, Pipaix, Thieulain, Tourpes, and Willaupuis.

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