He has spent time on loan from Wigan at Workington Town in Betfred League 1, and the Leigh Centurions and the Swinton Lions in the Championship.

[3][4][5][6] On 28 May 2022, Byrne played for Wigan in their 2022 Challenge Cup Final victory over Huddersfield.

[7] On 24 February 2024, Byrne played in Wigan's 2024 World Club Challenge final victory over Penrith.

[8] In the 2024 Good Friday game against arch-rivals St Helens, Byrne was given a straight red card for a dangerous high tackle in Wigan's 12-4 losss.

[9] On 12 October 2024, Byrne played in Wigan's 9-2 2024 Super League grand final victory over Hull Kingston Rovers.