Lidia Zamkow was born on 19 June or 15 July (sources vary), 1918 in Rostov-on-Don.

Until 1939 she was studying at the National Institute of Theatre Arts in Warsaw, and after World War II at the State Academy of Drama in Łódź (now Aleksander Zelwerowicz State Theatre Academy).

In 1944 she made her own actress' debut in the role of Isia in the Stanisław Wyspiański's Wedding on Polish Army Theatre in Lublin.

In the years of 1950–1952, 1957–1958 and the 1964–1972 she was an actress and director of Juliusz Słowacki Theatre in Kraków.

In later years Zamkow collaborated with many theatres in Poland and directed spectacles for Teatr TV.