[1] It is characterized by distal renal tubular acidosis that occurs as a result of bicarbonate wasting and the inability to excrete hydrogen ions.

[3] In order for the nephron to remove acid (hydrogen ions) from the body, it must pair it with ammonia to produce ammonium.

Therefore, health care providers will look at electrolytes and serum acid-base levels to determine if Lightwood-Albright Syndrome is the proper diagnosis.

[3] Clinical findings can include muscle wasting, vomiting, failure to thrive, fatigue, constipation, polyuria, and polydipsia.

[4] This treatment option utilizes alkali as a base to help equilibrate the amount of extra acid that is being retained in the body.