Her life story was told in the 1955 film I'll Cry Tomorrow, in which she was portrayed by Susan Hayward, who was nominated for the Academy Award for Best Actress for her performance.

[2] At the age of six, Roth was taken by her mother to Educational Pictures, where she became the company's trademark, symbolized by a living statue holding a lamp of knowledge.

According to Roth's autobiography, one of the highlights of the tour was meeting U.S. president Woodrow Wilson, who attended the girls' vaudeville act and later allowed them to ride with him briefly in his chauffeur-driven car.

Roth signed a seven-year contract with Paramount Pictures, where she appeared in The Love Parade (1929) with Maurice Chevalier and Jeanette MacDonald, The Vagabond King (1930), Paramount on Parade (1930), Honey (1930) (in which she introduced "Sing You Sinners"), Cecil B. DeMille's Madam Satan (1930) with Reginald Denny and Kay Johnson, Sea Legs with Jack Oakie and the Marx Brothers' second film, Animal Crackers (1930).

After leaving Paramount, Roth was cast by Warner Bros. in a supporting role in the 1933 women's prison film Ladies They Talk About starring Barbara Stanwyck.

[2] Friends accused her of forsaking Judaism; however, in her autobiography, Roth explained that although her parents had believed in God, she and her sister had not been brought up with a religious foundation.

In February 1953, Roth appeared on an episode of the television series This Is Your Life, hosted by Ralph Edwards, and related her story of alcoholism.

Roth wrote her autobiography I'll Cry Tomorrow with author-collaborator Gerold Frank in 1954, and a softened version of the story became the basis of a hit film of the same title the following year, starring Susan Hayward, who was nominated for an Academy Award.

Roth was married six times: to aviator William C. Scott (Willie Richards), judge Benjamin Shalleck, Mark Harris, Eugene J. Weiner, Edward Goldman (Vic) and Thomas Burt McGuire.

[citation needed] After suffering a stroke at her New York apartment in February 1980, Roth died at age 69 on May 12 at De Witt Nursing Home in Manhattan.