[5] After graduating from the San Diego Jewish Academy, Greenberg Call pursued higher education at the University of California, Berkeley, where she majored in political science and minored in public policy.

[7][8] In 2014, Greenberg Call covered events leading up to and during Operation Protective Edge as part of the Jewish United Fund's "Write on For Israel" journalism and advocacy program.

[12] From 2021 to 2022, Greenberg Call worked as a paralegal for Terris, Pravlik, and Millan LLP, a public interest litigation firm, assisting attorneys in civil rights and environmental cases.

[10] In February 2023, the United States Department of the Interior announced Greenberg Call as a political appointee, serving as Special Assistant to the Chief of Staff.

[14] She chose to resign on May 15, highlighting Nakba Day, which commemorates the mass displacement of Palestinians in 1948 that preceded the formation of the state of Israel.

[15][16] Her resignation letter criticized President Joe Biden's administration's support for Israel's actions in Gaza during the Israel–Hamas war, accusing him of exploiting Jewish people to defend U.S.