According to a reference in the Nekrolog of the Basilica of St. Castor in Koblenz, Archbishop Hetti of Trier (814–847) consecrated a church of Saint George in "Lympurgensis".

On 10 February 910, King Louis the Child issued a deed for the foundation of a Stift of canons, which the Gaugraf of Niederlahngau, Konrad Kurzbold (~ 885–948) had pushed for.

A lead reliquary from the 11th century, found in 1776 in the main altar in the form of a schematic model of a church, mentions a Graf (count) Heinrich as founder and builder of a new "templum", that being apparently the new basilica.

In the western part, the nave and the transept, and the walls up to the top of the level of the galleries, are remainders of the Early Romanesque basilica.

Most of the windows and the western portal were enlarged in Gothic style, but the vaults of the aisles of the nave are still of Romanesque type.

This seizure took place as part of the German mediatization, in which the House of Nassau received the Stift as compensation for the loss of the County of Saarbrücken on the left bank of the Rhine.

This diocese contained the territory of the Duchy and the free city of Frankfurt am Main, with the bishop's seat in the former collegiate church of St George, which was promoted to the rank of cathedral.

He was suspended on 23 October 2013, he was thereupon general vicar Wolfgang Rösch, who in turn was replaced by Georg Bätzing, who was elected to the office of Bishop by the Cathedral Chapter, confirmed by Pope Francis and Ordained by Arch-Bishop Woelki in 2016, since 2020 he has been Chairman of the German Bishops‘ Conference.

The tallest of these towers are on the western side and rise to a height of 37 m. They form the distinctive "twin-tower façade [de]" of the west front.

The most eye-catching stylistic element is a huge round window, surrounded by eight small rosettes, which forms a clear centre of the west front.

During restorations between 1872 and 1873, the polychrome exterior painting of the cathedral was removed (the colours were, previously, white, red, yellow-brown, black and a little green) and the stone was left bare.

The interior of the cathedral (nave and choir) is dominated by the completely undecorated buttresses, which reach all the way to the ceiling.

A. and M. Keller of Limburg converted the Baroque housing to a neo-Romanesque style between 1872 and 1877, while retaining Köhler's register.

The smaller Uhrglocke ("hour bell") from the year 1447 originally hung in the uppermost window of the south tower.

[5] The cathedral is used for concerts, such as the premiere of the oratorio Laudato si' on 6 November in 2016, composed by Peter Reulein on a libretto by Helmut Schlegel on a commission from the Diocese of Limburg.