He created the Broadway musicals In the Heights (2005) and Hamilton (2015), and the soundtracks for the animated films Moana (2016), Vivo, and Encanto (both 2021).

For his performance in the Disney+ live stage recording of Hamilton released in 2020, he received a Golden Globe and Primetime Emmy Award nominations.

[22][23] Miranda has one older sister, Luz, who is the Chief Financial Officer of the MirRam Group, a strategic consulting firm in Government and Communications.

[29] Miranda wrote the earliest draft of what would become his first Broadway musical, In the Heights, in 1999, during his sophomore year of college at Wesleyan University.

[35] Miranda rejoined the Broadway cast as Usnavi from December 25, 2010, until the production closed on January 9, 2011, after 29 previews and 1,185 regular performances.

He wrote Spanish-language dialogue and worked with Stephen Sondheim to translate into Spanish song lyrics for the 2009 Broadway revival of West Side Story.

[39] During these years, Miranda worked as an English teacher at his former high school, wrote for the Manhattan Times as a columnist and restaurant critic, and composed music for commercials.

The group created a limited television series for Pivot in 2014[42] and made its Broadway debut[43] on October 2, 2019, at the Booth Theatre.

[46][47] It played a limited engagement on Broadway at the St. James Theatre, beginning previews on July 12, and officially opening on August 1, 2012.

Inspired by the book, he wrote a rap about Hamilton that he performed for the White House Evening of Poetry, Music, and the Spoken Word on May 12, 2009, accompanied by Alex Lacamoire.

[58] Chernow and Miranda received the 2015 History Makers Award from the New York Historical Society for their work in creating the musical.

[59] The show began previews on Broadway in July 2015 at the Richard Rodgers Theatre and officially opened on August 6, 2015,[60] earning positive reviews.

[70] In 2017, he announced that he would reprise the role for one night in celebration of President Obama's commutation of the sentence of Oscar López Rivera.

[76][77] In a review, Chris Jones praised "deeper on-stage emotions" in Miranda's reprisal, as well as improved vocal and dance technique than on Broadway.

[78] In March that same year he played King Arthur in a benefit concert of Camelot at Lincoln Center opposite Solea Pfeiffer and Jordan Donica.

[113] However, the project was canceled in March 2011,[114] reportedly due to the fact Universal was looking for a "bankable Latino star" like Shakira or Jennifer Lopez instead of unknown actors.

"[120] Miranda also served as producer and acted alongside Anthony Ramos,[121] Corey Hawkins,[122] Leslie Grace,[123] and Jimmy Smits.

[130][131] The same year, Miranda starred as the titular character in addition to providing eleven songs and serving as an executive producer for Vivo, a Sony Pictures Animation film directed by Kirk DeMicco which was released on Netflix in August 2021.

[132][133][134] Miranda agreed in 2016 to serve as executive producer and composer of Lionsgate's film adaptation of The Kingkiller Chronicle by Patrick Rothfuss, as well as a tie-in television series.

For Sesame Street, he occasionally played roles and sang the theme song to the recurring segment Murray Has a Little Lamb.

[143] He later appeared in the CBS sitcom How I Met Your Mother, in an all-verse episode titled "Bedtime Stories" that aired in November 2013.

[145] Miranda hosted Saturday Night Live on October 8, 2016, and played himself in two episodes of Curb Your Enthusiasm in 2017, receiving Emmy Award nominations for both appearances.

Miranda, in collaboration with Brittany Howard, Daveed Diggs, Kristen Anderson-Lopez, and Robert Lopez, wrote the lyrics for the song "Checks and Balances", which was sung by Benjy Brooke for the 2021 Netflix animated series We the People.

[158][159] His son Sebastian was named after the Jamaican crab from The Little Mermaid, one of his favorite films, the reason for which he took the job of composing the music for the live-action version.

Backstage, the mother of Residente and ILE revealed their connection to Gilberto Concepción de Gracia, founder of the Puerto Rican Independence Party.

[173] Miranda was particularly active in the wake of Hurricane Maria's devastation in Puerto Rico,[10][11] and by December 2017, proceeds from his song "Almost Like Praying" helped the Hispanic Federation raise $22 million for rescue efforts and disaster relief.

The Miranda family donated approximately $1 million to bring the University of Puerto Rico theater up to par in order to use it as the venue for the musical's performance in January 2018.

After tickets sold out in two hours for the three-week run, producers decided to move out of the university venue due to warnings of potential disruptions by a university workers' labor organization, and move the already-installed set to the Luis A. Ferré Performing Arts Center in Santurce, where the performances ran from January 11 to January 27.

[182] During the post show, Miranda met with protestors explaining that he had seen PROMESA as the only bipartisan option for the debt crisis previously, he does not support the austerity measures introduced and that he believes full debt-relief should now be pursued.

[194] He received the honorary degree of Doctor of Humane Letters in 2015 from his alma mater, Wesleyan University,[195] and gave their commencement address.