"[1] According to The Star newspaper, Lira is currently considered the foremost adult contemporary female solo artist in South Africa.

[citation needed] She has appeared in major ad campaigns and been an ambassador for Audi, Shield, Samsung, MTN and BlackBerry.

As an undergraduate student, Lira studied Accounting and used her skills to exchange for recording time at a local studio, resulting in her first demo at the age of 18.

The title track even knocked Beyoncé's single "Dangerously in Love" off the charts[5] The following year, she left 999 Music and teamed up with keyboardist Victor Mngomezulu, bassist Tshepo Sekele, and producer Robin Kohl.

[7] The album sold Triple-Platinum by the Recording Industry of South Africa while the single received the SAMA Award in 2008 for most downloaded song.

Filmed before a live audience at the Carnival City Casino, the production employed 10 RED digital video cameras – a first globally – and was released the same year.

Nine million South Africans tuned into the concert's telecast and subsequently, the DVD reached three-times platinum when it was released in November 2010.

[10] The soundtrack to the DVD released in October 2009 was certified Platinum In the summer of 2010, she joined a lineup of artists that included Alicia Keys, Shakira, K'Naan and John Legend, at the FIFA World Cup Kick-Off Concert performing a rendition of "Pata Pata," a hit song originally recorded by the late Miriam Makeba.

[11] She made her cinematic debut as the support lead in the Antonio Falduto-directed drama The Italian Consul (Il Console Italiano).

Lira stars opposite Italian actress Giuliana de Sio – as well as Edwin Angless and Anna Galiena, while the film centres on the trafficking of girls in Europe.

Songs included "Call Me," "Abba", "Get into Action", "Mali", "Phakade," and "Be My Friend", while incorporating sounds of funk, ragga, urban, soul and traditional African.

"[16] On 13 December 2014, Lira was the special guest act for American Neo-Soul star Jill Scott, in a one-night-only concert in Johannesburg.

[20][21][22] On 1 September 2022, Lira made her first public appearance since her stroke, attending the launch of fellow musician, Tamara Dey's, new single, Disco Therapy.