Lis Smith (born October 15, 1982) is an American political strategist affiliated with the Democratic Party.

After McCaskill's win, she joined the 2007 Kentucky gubernatorial campaign of Bruce Lunsford and Greg Stumbo as traveling press secretary.

After winning the election, the candidate joined the Independent Democratic Conference (IDC), and Smith consulted briefly for the group.

[13][14] Smith met Pete Buttigieg on the recommendations of Axelrod and O’Malley when he was considering running for Democratic National Committee chair in 2017 and became a consultant for the campaign.

[9] Smith was credited with implementing a campaign strategy that emphasized one-on-one interactions between Buttigieg and the press which helped raise his profile from the mayor of the fourth-largest Indiana city to a top-tier presidential candidate.

[9][15] She later modeled a New Hampshire bus trip off of John McCain's Straight Talk Express during his 2000 presidential campaign in which reporters were invited on board to travel and question the candidate.

[19] In 2021, Smith worked closely with then-governor Andrew Cuomo, and advised him on how to respond to the sexual harassment allegations against him.

A report by New York Attorney General Letitia James showed that Smith was working behind the scenes to protect Cuomo from the allegations.

[26][27][28] Philip Elliott of Time praised its transparency and wrote that it "may just rewrite the template for what a political memoir can be.

[31][32] In March 2024, the Democratic National Committee selected Smith to lead communications, opposition research and legal challenges as part of a team focused on combatting independent and third-party candidates in the 2024 presidential election.

[38][39][40] She also has an active social media presence, through which she addresses political topics and factchecks statements by Republican politicians such as Mitt Romney.