LoCicero played Miral Paris in the 2001 series finale of Star Trek: Voyager,[3] as well as the recurring role of Nina Shaw on the sitcom Raising Dad in 2002.

[6] Around this time she auditioned for the character Lois Cerullo on General Hospital, and was offered the recurring role of Kathryn Fitzgerald on One Life to Live.

When One Life to Live executive producer Frank Valentini later offered LoCicero the contract role of Sonia Toledo, she accepted it.

However, after head writer Michael Malone was replaced by Dena Higley in late 2004, LoCicero and fellow cast member Javier Morga (Tico Santi) were written off the series.

[2] On June 2, 2015, LoCicero announced on her official Twitter account that she gave birth to a daughter, Verity Marion, on May 30.