At the federal level, the Democratic Party's majority in both houses of the 117th United States Congress was cited by Politico as a likely precondition for federal legalization in 2021, with the SAFE Banking Act likely to pass.

Allows sales by April 2022 and regulation under new Rhode Island Cannabis Control Commission.

It was the first time a legalization measure was cleared for a floor vote in either chamber of the Rhode Island legislature.

[119] VA Medicinal Cannabis Research Act of 2021 Common Sense Cannabis Reform for Veterans, Small Businesses, and Medical Professionals Act MORE Act States Reform Act On February 18, 37 members of Congress – including two members of the Congressional Cannabis Caucus, Barbara Lee and Earl Blumenauer, who were the authors – formally asked President Biden to fulfill a campaign promise by issuing a mass presidential pardon to Americans convicted of nonviolent cannabis crimes.

[185][186] On November 10, a group of senators led by Elizabeth Warren wrote a letter to President Biden requesting him to issue pardons for individuals convicted of nonviolent cannabis crimes, referencing his campaign promise to "zero out" such convictions.