List of Billboard Global 200 number ones of 2021

In addition, two other number-one singles, "All I Want for Christmas Is You" by Mariah Carey and "Dynamite" by BTS, had each previously hit number one in 2020.

Sixteen artists reached the top of the chart, with thirteen—Olivia Rodrigo, Drake, Rosé, Justin Bieber, Daniel Caesar, Giveon, Lil Nas X, The Weeknd, Ed Sheeran, the Kid Laroi, Coldplay, Adele, and Taylor Swift—achieving their first number-one single.

In addition, two other number-one singles, "All I Want for Christmas Is You" by Mariah Carey and "Dynamite" by BTS, had each previously hit number one in 2020.

Thirteen artists reached the top of the chart, with eleven—Olivia Rodrigo, Rosé, Justin Bieber, Daniel Caesar, Giveon, Lil Nas X, Ed Sheeran, the Kid Laroi, Coldplay, Adele, and Taylor Swift—achieving their first number-one single.

Bieber and the Kid Laroi's song "Stay" is tied with Olivia Rodrigo's "Drivers License" as the longest reigning number-one song of 2021, each with nine weeks atop the chart.

Canadian singer Justin Bieber topped the Global 200 for 13 weeks and the Global Excl. US for 14 weeks, aided by two number-one singles " Peaches " and the Kid Laroi collaboration " Stay ".