The series was set in a Roger Rabbit-like world where "toons" and humans co-exist.
He was made the junior partner of Detective Lucky Piquel, a grim and ill-tempered human who hates toons.
Throughout the series, the pair work together to solve crimes in the Hollywood, Los Angeles, California region.
Bonkers repeatedly tried to win Piquel's praise, but usually just ended up ruining missions with his antics.
At the end of the "Lucky" episodes, Bonkers was given a new partner, the attractive Sergeant Miranda Wright.
The Rubber Room Song segment originally belongs to the previously produced and the later aired episode "Casabonkers".
The resultant "international" order (excluding the compilation episodes) perhaps most closely reflects the series' in-universe chronology.
Bonkers joins the Hollywood Police with a partner, Lucky Piquel on a case for missing Toons, snatched by a criminal called 'The Collector'.
Amateur imposter Babyface, a former child star, is replacing Mickey in addition to a bulldog as Pluto.
The temporate mascots of Wheat Crunchies Turbo, Banshee and Kapow are the culprits and set up Slap, Sniffle and Flop, but Bonkers and Piquel arrive to stop them and save the CEO.
Piquel is having a nervous breakdown being unable to nab the mole thief, who is stealing works of priceless art and he is haunted by the sight of him.
Failed attempts at curing Piquel's stress, turn him into an ape until he accidentally lands on the mole.
With the help of Dr. Ludwig Von Drake, Bonkers manages to exchange good dreams for Baa-bara in return for ceasing her invasion.
Al Vermin, Catcha, Miranda and Flaps all try to get it from Bonkers until the original owners come to reclaim it.