The first—and least powerful—Xeon to support VT-d was the E5502 launched Q1'09 with two cores at 1.86 GHz on a 45 nm process.
[2] Many or most Xeons subsequent to this support VT-d. See Advanced Search: feature=VT-d and segment=server for the full list.
(1) 48 GB with CPU as xeon x5680 and 8GB DIMMs List of AMD and AMD-based hardware that supports IOMMU.
[101] Please note that just because a motherboard uses a chipset that supports IOMMU does not mean it is able to and the bios must have an ACPI IVRS table to enable the use of it.
Note: Newer AMD cards no longer have FLR bug as of 2021.