List of Preacher story arcs
Reverend Jesse Custer, a tough and principled Texan preacher who has lost his faith, is possessed by a mysterious entity called Genesis—a conscienceless offspring of an angel and a demon whose power may rival that of God Himself.
Meanwhile, in Heaven, a quorum of angels, trying desperately to keep things from falling apart, decide to send the Saint of Killers—an immortal, unstoppable killing machine—to Earth with orders to recapture Genesis at any cost.
Upon their return to the States, a grateful Cassidy tells Jesse his life's story: how he fought in the 1916 Easter Rising in Ireland, how he was assaulted by a bog-hag outside of Dublin and turned into a vampire, and how he arrived penniless in America and began his long love affair with New York City.
The trio arrive in New Orleans, where an old friend of Cassidy's—a voodoo priest—agrees to help Jesse unlock the secrets locked deep within Genesis, including the story of the Saint of Killers.
Ultimately the trio leave New Orleans without answers and decide to travel to the American Southwest, but not before the priest warns Tulip that Cassidy is thoughtless and weak, and not to be trusted.
He also discovers that the acerbic, one-armed owner of the local bar is his long lost (and presumed dead) mother, Christina (known in the town as Jodie).
Before he leaves, having broken Quincannon's hold on the town and restoring it to freedom, Christina gives Jesse the one possession of his father's that she has kept: his Medal of Honor.
Later, Jesse takes the peyote he kept with him, which causes him to remember the events in Monument Valley after his fall: how God saved him from death and asked him outright to give up his quest.
Meanwhile, Arseface becomes a music sensation when a record producer recruits him and convinces him to release a cover of the Alanis Morissette song "You Oughta Know".
Finally, Herr Starr kills Eisenstein, the remaining figure standing between him and complete control over the Grail, but at the cost of his genitals.
Originally a retired gunfighter in the mold of William Munny, his wife and daughter were stricken with fever in their remote mountain cabin ten years after he gave up his life as a ruthless bounty hunter and murderer.
He returns to Ratwater, but is killed before he can take his vengeance; finding himself in Hell, however, does nothing to quell his hatred, making him immune to the Devil's torture.
The Angel of Death, in the area for a poker game and weary of his position, offers the gunfighter the job of Saint of Killers, under the command of none but God.
This entire sequence of events is later revealed to be the work of God, who put the outlaws in his way in order to turn his already intemperate disposition into the all-encompassing rage needed for a Saint of Killers.
