This is a list of destroyers of the United States Navy, sorted by hull number.

CG-47 Ticonderoga and CG-48 Yorktown were approved as destroyers (DDG-47 and DDG-48) and redesignated cruisers before being laid down; it is uncertain whether CG-49 Vincennes and CG-50 Valley Forge were ever authorized as destroyers by the United States Congress (though the fact that the DDG sequence resumes with DDG-51 Arleigh Burke argues that they were).

The DLG sequence was deactivated in the 1975 fleet realignment, most DLGs and DLGNs were reclassified as CGs and CGNs, 30 June 1975.

The guided missile destroyer sequence has three irregularities: four DDGs are numbered as if they were Destroyers in the main sequence (DDG-993, -994, -995 and -996), two were redesignated as guided missile cruisers (CG) (DDG-47 and DDG-48), and two numbers were skipped (DDG-49 and DDG-50).

This article incorporates text from the public domain Dictionary of American Naval Fighting Ships.