List of United States senators from Mississippi

Mississippi was admitted to the Union on December 10, 1817, and elects senators to class 1 and class 2.

Its current senators are Republicans Cindy Hyde-Smith and Roger Wicker.

As of February 2022, 51 people have served as U.S. senators from Mississippi.

John C. Stennis was Mississippi's longest-serving senator (1947–1989).

Mississippi last elected a Democrat in 1982, and both seats have been occupied by the Republicans since 1989.