List of United States senators from South Carolina

South Carolina ratified the United States Constitution on May 23, 1788.

Its Senate seats were declared vacant in July 1861 owing to its secession from the Union.

The state's current U.S. senators are Republicans Lindsey Graham, serving since 2003, and Tim Scott, serving since 2013.

Strom Thurmond was the state's longest-serving senator (1954–1956, 1956–2003).

Stephen Decatur Miller Daniel Elliott Huger