The following is a list of ambassadors of the United States to Ghana.

The embassy in Accra was established March 6, 1957, with Donald W. Lamm in charge as chargé d'affaires.

President Joe Biden nominated career U.S. diplomat and Acting Assistant Secretary/Principal Deputy Assistant Secretary of the Bureau of Energy Resources Virginia E. Palmer for the position on June 2, 2021.

Senior Staff Of Travel Relations Peter Asante Smith