This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.
All drugs listed are approved specifically for major depressive disorder unless noted otherwise.
Selective serotonin reuptake inhibitors include: Serotonin–norepinephrine reuptake inhibitors include: Serotonin–dopamine reuptake inhibitors include: None currently marketed Serotonin–norepinephrine–dopamine reuptake inhibitors include: Serotonin modulators and stimulators include: Serotonin antagonist and reuptake inhibitors include: Norepinephrine reuptake inhibitors include: Norepinephrine–dopamine reuptake inhibitors include: Tricyclic antidepressants include: Opipramol (Insidon), tianeptine (Stablon, Coaxil) and amineptine (discontinued; formerly Survector, Maneon) are chemically TCAs but are pharmacodynamically atypical, and are therefore grouped elsewhere.
Tetracyclic antidepressants include: Mianserin, mirtazapine, and setiptiline are also sometimes described as noradrenergic and specific serotonergic antidepressants (NaSSAs).
Monoamine oxidase inhibitors include Discontinued/withdrawn Discontinued/withdrawn These drugs are sometimes described as reversible inhibitors of MAO-A (RIMAs).