List of important publications in chemistry

[1][2][3][4] Some factors that correlate with publication notability include: Description: Boyle, in the form of a dialogue, argued that chemical theories should be firmly grounded in experiment before their acceptance, and for the foundation of chemistry as a science separate from medicine and alchemy.

Boyle, in this book, became the first to argue that experiment should form the basis of all theory, a common practice in chemistry today.

He also expounded on a rudimentary atomic theory and the existence of chemical elements beyond the classic earth, fire, air, and water.

Description: Contains synthetic models selected by world-renowned experts, with full experimental procedures and background information.

Importance: Breakthrough, Influence Description: A comprehensive reference for the usage of protecting groups in organic synthesis.

Importance: The concepts outlined in this text changed the field of organic chemistry and ushered in the frontier molecular orbital theory approach toward understanding reactions.

A standard postgraduate text book for the study of total synthesis and a valuable reference work for experts.

Description: Unique very advanced and comprehensive coverage of every element known at the time by chapter describing all known compounds yet discovered or synthesised.

Importance: The most comprehensive one-volume text on inorganic chemistry available; a worthy successor to Taylor and Irving (see above).

Importance: This massive text by outstanding research workers begins with simple systems and proceeds logically to the more complex phenomena of physical chemistry.

They conclude with the sly remark: "It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material."

Importance: Topic creator, Breakthrough, Influence Description: The structure of the potassium channel is determined by X-ray crystallography.

Access to the structure provided answers to central questions in biology, regarding the movement of ions across the cell membrane.

Importance Breakthrough, Influence Description: Starting with examples comparing two sets of experimental data, this text explains variance and the calculation of standard deviations, degrees of freedom, the null hypothesis and the "Student's" t-Test by William J. Gosset.

Written by a chemist who made major contributions to the physical chemistry of polymers, for which he won the Nobel prize in 1974.

The authors generally present the material using a ground up approach that emphasizes fundamental principles of thermodynamics and kinetics.

[18] Mario J. Molina and F. S. Rowland, Nature 249, 810–812 (1974) Description: This paper warned of the danger of ozone depletion due to man-made chlorofluorocarbons.

This was because they clearly identified unacceptable environmental hazards in a large, economically important sector.” [2] Description: Paper applied the thermodynamic theory of steam engines to atomic level chemical reactions; i.e., it established equilibrium criteria necessary to predict the thermodynamic tendency of chemical reactions at constant temperature and pressure.

Importance: Topic creator; historian Bill Bryson states, in his A Short History of Nearly Everything, that Gibbs’ Equilibrium paper is "the Principia of thermodynamics".

Importance: This is a good introduction to the subject, but has particular significance in the way it describes how the theory throws new light on old chemical concepts such as electronegativity.

Importance: First demonstration of ab-initio molecular dynamics, where the forces are computed on-the-fly by means of quantum mechanical electronic structure calculations.

Description: Selected articles:[citation needed] "Supramolecular Medicinal Chemistry: Mixed-Ligand Coordination Complexes".Mol.

Importance: Breakthrough, Influence Description: A great overview of the theory, methodology, and techniques of drug design.