The current mayor is Chiara Frontini, a centre-right independent, who took office on 27 June 2022.

According to the Italian Constitution, the Mayor of Viterbo is member of the City Council.

The Mayor is elected by the population of Viterbo, who also elects the members of the City Council, controlling the Mayor's policy guidelines and is able to enforce his resignation by a motion of no confidence.

The Mayor is entitled to appoint and release the members of his government.

[1] Since 1995, under provisions of new local administration law, the Mayor of Viterbo is chosen by direct election.