List of number-one singles of 2001 (Australia)

In 2001, 16 acts achieved their first number-one single in Australia, either as a lead artist or featured guest, including Shaggy, Mýa, LeAnn Rimes, Lifehouse, Scandal'us, and Alien Ant Farm.

Shaggy, Rayvon, Scandal'us, and Kylie Minogue were the only acts to have earned a number-one debut single this year.

Shaggy's "Angel" and Alien Ant Farm's "Smooth Criminal" were the longest-running number-one singles of 2001, remaining in that position for eight weeks.

The second-longest run at number-one was "Can't Fight the Moonlight" by Leann Rimes, whose streak on the top spot reached six weeks.

Songs that peaked at number two include I'm Like A Bird by Nelly Furtado, Whole Again by Atomic Kitten, Don't Stop Movin' by S Club 7, Ms. Jackson by Outkast, How You Remind Me by Nickelback, Let's Get Married by Jagged Edge and Strawberry Kisses by Nikki Webster Songs that peaked at number three include All Rise by Blue, Dance With Me by Debelah Morgan, Bette Davis Eyes by Gwyneth Paltrow, Purple Pills by D12 and I'm Real by Jennifer Lopez Other hit songs included Butterfly by Crazy Town (4), With Arms Wide Open by Creed (4), Let Me Blow Ya Mind by Eve feat.

Reggae singer Shaggy had two number-one singles for 12 weeks on the top spot in a calendar year.
LeAnn Rimes scored her first Australian number-one single with " Can't Fight the Moonlight ", which topped the chart for six weeks.
Lifehouse gained their first number-one single in Australia with their debut single " Hanging by a Moment ", which stayed at the top spot for five consecutive weeks.
Mýa reached the top spot with two singles, as the lead artist on " Case of the Ex ", which topped the chart for two weeks, and as one of four acts on " Lady Marmalade ", which stayed at the top spot for three consecutive weeks.
Kylie Minogue scored her seventh Australian number-one single with " Can't Get You Out of My Head ", which topped the chart for four consecutive weeks.