The following is a List of senators of Seine-et-Oise, people who have represented the former department of Seine-et-Oise in the Senate of France.
The department was dissolved in 1968, with most of its territory becoming the new departments of Essonne, Yvelines and Val-d'Oise.
Senators served one term under the French Fifth Republic, from 1959 to 1968, after which the department was dissolved.