This article lists the individuals to have served as Main Opposition Leader of Turkey, since the inception of the republican period in 1923.

The Main Opposition Leader (Turkish: Ana Muhalefet Lideri) is the leader of the largest political party in the Grand National Assembly that is not in cabinet.

Except for two brief periods (1924–25 and 1930), there were no opposition leaders in the one-party period.

Furthermore, there were no opposition leaders during the periods of military dictatorships in the multi-party period (1960–61 and 1980–83).

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