The southwesternmost area is Devínska Kobyla in Bratislava, and the northeasternmost area is the Čachtice Carpathians at the town of Nové Mesto nad Váhom and the village of Čachtice in the Trenčín Region.

Deciduous trees are dominant, with the beech, linden, European ash, and sycamore maple being most widespread.

The Little Carpathians PLA is the only place in Slovakia where some plants grow, for example, Ruscus hypoglossum and Rhamnus saxatilis.

Notable species of birds are represented by the rock thrush, northern wheatear, black stork, European honey buzzard, short-toed eagle, Eurasian eagle-owl, long-eared owl, and European nightjar.

The Landscape Area is home to the largest population of the saker falcon in Slovakia.