Each episode typically begins with a short comedy sketch, which inspires Little Howard to blow a loud animated klaxon and ask a "big question" on a related topic.

After a credit sequence involving an animated monkey song-and-dance routine, the remainder of the programme investigates possible answers to the big question, using a combination of research, expert advice, fantasy, and song.

Similarly, a frequent element throughout the series is the use of humorous pop culture references to appeal to an adult audience, and which would fly over younger viewers' heads.

Actors who appeared in series 2 included David Schneider,[7] Sy Thomas,[8] Lucy Porter,[9] Siân Lloyd,[10] Jarred Christmas,[11] Tim Brooke-Taylor, Marek Larwood, Barney Harwood,[12] and Andre Vincent.

Actors who appeared in series 3 included: Rusty Goffe, Ben Moor,[15] Daniel Hill,[16] Chris Cox,[17] Doc Brown, Trevor Neal,[18] and Thomas Nelstrop.