Little Iodine is a 1946 American comedy film directed by Reginald Le Borg and written by Richard H. Landau.

The film stars Jo Ann Marlowe, Marc Cramer, Eve Whitney, Irene Ryan, and Hobart Cavanaugh.

Little Iodine (Marlowe) stays true to her comic strip nature in this film, where she does her best to break up the marriage of her parents “the Tremblechins” (Cavanaugh and Ryan), ruin a romance between Janis and Marc (Whitney and Cramer), and cost her father his job.

Unlike her comic-based character, however, Iodine has a change of heart and sets out to right the wrongs.

They wanted to get a new audience in at United Artists, so [producer] “Buddy” Rogers came up with the idea.