The Little Russia Office (Russian: Приказ Малыя Россіи) was a Muscovite state agency (Prikaz) and administrative body of the Tsardom of Muscovy in charge of affairs connected with the Cossack Hetmanate and the Left-bank Ukraine.
Conditions of the office were expressed in articles (or statutes; Russian: статьи) which were concluded with every newly elected Hetman.
The creation of dual hetmanship conditionally divided Ukraine along the Dnieper which later in 1667 saw its virtual and legal realization at the Treaty of Andrusovo.
It controlled the Hetman and its officer council implementing a prikase-voivode system of the Russian administration in Ukraine.
The prikase prevented any attempts that were undertaken to succeed Ukraine from Russia in its early stage.