"Little Sister Leaving Town" is a song by British singer-songwriter Tanita Tikaram, released in 1990 as the second single from her second studio album The Sweet Keeper.

"[3] Everett True of Melody Maker commented: "Well, this ain't so bad – the cello's keen, and suits her mournful countenance just peachy.

"[5] In a review of The Sweet Keeper, Robin Denselow of The Guardian described the song as "slinky and finger-clicking" which "head[s] towards soulful Van Morrison territory.

"[6] Holly Crenshaw of The Atlanta Constitution described the song as "typical of the album's feel" and added: "Ms. Tikaram slowly uses the dynamics of her deep voice and evocative instrumentation to build up to an emotional chorus.

"[8] Brant Houston of the Hartford Courant commented: ""It All Came Back Today" and "Little Sister Leaving Town" are easily two of the best cuts, both with memorable choruses and each elegiac and moving.