The parish is bounded to the northwest by the River Swere and a road between Little Tew and Hook Norton, to the north by a tributary of the River Cherwell and to the south by an ancient drovers' road called Green Lane.

In 1441 Henry VI seized the priory and its estates and gave them to Eton College, which sold most of its land at Little Tew in 1921.

However, in 1545 the seat of the Diocese of Oxford was transferred from the former Osney Abbey to the former St. Frideswide's Priory and the manor at Little Tew was returned to the Crown.

[1] There is a tradition that Little Tew had a medieval chapel before the English Reformation, but no physical or definite documentary evidence is known to prove this.

[1] The first report of Baptists in Little Tew is from 1771 and one villager registered his house as an Anabaptist meeting place in 1778.

[7] The Baptist chapel was rebuilt in 1871, with a stepped gable and Perpendicular Gothic style windows.

It may have been on the same site as a windmill recorded near Lodge Farm in 1742, south of the village on the road to Church Enstone.

[7] It was extended in the 16th century and is now internally reordered as two cottages but it retains its medieval screens passage.

Little Tew continued to farm under an open field system until an Act of Parliament enabled its lands to be enclosed in 1794.

[1] In 1862–63 a new schoolhouse and master's house and set of three almshouses were built, all designed by Charles Buckeridge.