Littleton is a census-designated place (CDP) in Wetzel County, West Virginia, United States.

[1] According to the United States Census Bureau, the town had a total area of 0.7 square miles (1.7 km2), all land.

There were 98 housing units at an average density of 544.0 per square mile (210.2/km2).

30.1% of all households were made up of individuals, and 16.4% had someone living alone who was 65 years of age or older.

About 52.7% of families and 64.6% of the population were below the poverty line, including 83.5% of those under the age of eighteen and 30.8% of those 65 or over.