After making her debut in 2005, Fries has gone on to appear in almost 40 acting roles, the majority of which have come in German films and TV series such as Zurich, Add a Friend, and The Wave.

[7] Fries performed in the German made-for-television film She Deserved It [de] (2010) as an aggressive, frustrated teenager named Linda who tortures one of her peers.

[8] In 2013, she starred in the German tragicomedy Zurich (original title Und morgen Mittag bin ich tot).

According to Fries, she prepared for the role by meeting with a patient with the disease, in addition to running up stairs while breathing through a straw.

[4] In late 2018, Fries began the six-month shoot for the third season of Babylon Berlin which premiered in Germany in January 2020 and arrived on Sky Atlantic in March 2020.