Cleonini Lixini Rhinocyllini Lixinae is a subfamily of true weevils,[1] included in the Molytinae in many older treatments.

Several species are used in biological control of invasive weeds, namely knapweeds (Centaurea).

Characteristics include tarsal claws that are fused at the base, and labial palps are short and telescoping.

Bearing in mind modern geographical distribution of Lixinae and its feeding links, it is considered to be that this subfamily appeared in Euroasian lands, when the area of Tethys Ocean demenished.

Probably, lixine weevils formed as group in the arid conditions of the deserts of Ancient Mediterranean.