A Democrat, she represents District 28, consisting of the East Side of Manhattan, in the New York State Senate.

[5] She is married to John E. Seley, a professor of urban planning and geography at The City University of New York Graduate Center and Princeton's Woodrow Wilson School of Public Affairs.

[11] In 2021, Krueger was one of two members of the senate to vote against a bill designating baseball as the official state sport of New York.

[12] Krueger is a member of the Vote Blue Coalition, a progressive group and federal PAC created to support Democrats in New York, New Jersey, and Pennsylvania through voter outreach and mobilization efforts.

[13] Late November 2024, Krueger made proposals to counter the incoming Trump administration encouraging New York and a bloc of liberal northeast states to join Canada.