Elizabeth Anne Velásquez (/ˈlɪzi vəˈlæskɛz/; born March 13, 1989) is an American motivational speaker, activist, writer, and YouTuber.

She was born with an extremely rare congenital disease called Marfanoid–progeroid–lipodystrophy syndrome that, among other symptoms, prevents her from accumulating body fat and gaining weight.

[20][21] Ever since she was dubbed the "World's Ugliest Woman" in a video posted on YouTube in 2006, when she was 17, Velásquez has spoken out against bullying.

In January 2014, she gave a TEDxAustinWomen Talk titled "How Do YOU Define Yourself",[22] and her YouTube videos have received over 54 million views.

Velásquez has also written two books directed at kids, which share personal stories and offer advice.

[29] A documentary film titled A Brave Heart: The Lizzie Velásquez Story premiered at SXSW on March 14, 2015.